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Today, we’ve got Marc Andreessen explaining why the real AI boom hasn’t even started, OpenAI’s Jony Ive device slipping to 2027 (and losing its name), and Deep Research getting a serious upgrade with GPT-5.2 and data connectors.

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Breaking News

The Latest AI Developments

Windows users finally get the full Claude desktop experience. Cowork brings multi-step task execution, local file access, and MCP connectors to the platform. Same capabilities that macOS has had, now with full feature parity. If you’ve been running Claude through the browser on Windows, this changes things.

Deep Research just leveled up. It now runs on GPT-5.2, pulls from Google Drive and SharePoint in read-only mode, and lets you whitelist specific domains. You can also steer the research mid-run and export finished reports to Markdown, Word, or PDF. If you’ve been waiting to plug it into your workflow, now’s the time.

Warp has shipped Oz, a new layer for running AI coding agents in isolated cloud environments. You can schedule runs, pipe in secrets, and get full logs without cluttering your local machine. Think of it as mission control for your SWE agents. The scheduling alone is great for anyone running agents overnight.

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Interesting AI

Isomorphic Labs‘s Drug Design Engine benchmarks are turning heads. It more than doubles AlphaFold 3’s accuracy on the hardest protein-ligand predictions, the ones furthest from training data, where generalization matters most.

But structure prediction is only part of it. IsoDDE can identify hidden binding pockets on proteins using only the amino acid sequence. It predicted the location of a recently discovered “cryptic site” on cereblon that took researchers 15 years to find experimentally. On a computer. In seconds.

This is the kind of capability that rewrites how drugs get designed. Still internal to Isomorphic for now, but the technical report is public.

Notable AIs

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AI Finds

Beyond the Feed

Dwarkesh Patel digs into what scaling laws are really buying us. Capabilities? Reliability? Agency? The answer might change how you think about progress.

Amanda Askell is the philosopher Anthropic trusts to shape Claude’s ethics. This profile explains how one person’s decisions ripple through millions of conversations.

Court filings reveal Jony Ive’s AI device won’t reach customers until March 2027. It also won’t be called “io.” Back to the drawing board on the name, apparently.

Marc Andreessen sits down for a wide-ranging conversation on AI. His take? We’re still in the warm-up phase and the real AI boom is coming.

HBR looked at what happens when teams adopt AI. The result? Higher throughput expectations, not more free time. The treadmill just got faster.

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Prompt of the Day

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That’s a wrap for today! We hope these AI insights give you something to think about. Reply and let us know what stood out most. Don’t forget to share your favorite finds with friends, family, and colleagues! 🦾

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